We are enhancing our
understanding
of the genetic basis for
human diseases

What can we help you with

Microinjection

Model Generation

Genetically modified rodent models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. 
Phenotyping

Phenotyping

The genomes of humans, mice and other species have been completely sequenced, yet the knowledge of genome sequences as such does not shed light on questions concerning the functions of these sequences. 

Animal Facility

The Animal Facility Module of the Czech Center for Phenogenomics is based on the latest advances in housing, breeding and care of laboratory mice and rats. 
Mouse tumors

Preclinical Testing

The Czech Centre for Phenogenomics can offer a very broad portfolio of highly standardized assays useful for preclinical studies on rodents including established disease models. 

From our Twitter

Latest News

16. 10. 2025

Open Call for Proposals: Nominate Your Gene or Disease

The Czech Centre for Phenogenomics (CCP) is excited to announce the 3rd Call for Nomination of Genes or Diseases within the RD-Factory program. This continuous call invites proposals from scientists, clinicians, patient groups, and affected families, aiming to: More information – Rare Disease Factory

07. 07. 2025

Postdoctoral Scientist / Junior Researcher

We are seeking a motivated postdoctoral scientist or junior researcher focused on Prader-Willi syndrome research and therapy development.

07. 07. 2025

Experienced Researcher / Postdoctoral Scientist

To strengthen our team working on preclinical R & D projects related to skin diseases, we are seeking an experienced researcher or postdoctoral scientist.

About Czech Centre for Phenogenomics

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.

Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.