News
Advances in modelling COVID-19 in animals
In a recently published review article, experts from the Czech Centre for Phenogenomics summarised all generated SARS-CoV2-related animal models to date, evaluated their suitability for COVID-19 research, and addressed the current and future state of the importance of animal models in this field. Nickl P, Raishbrook MJ, Syding LA and Sedlacek R (2022) Advances in… Read more
Preclinical testing of venom-derived compounds – open call for services
In the framework of the EUVEN COST Action the unique phenotyping infrastructure Czech Centre for Phenogenomics (CCP) will support researchers in searching for the novel utilization of venom-derived compounds and identifying their translational potential and identifying physiological functions of toxin compounds. CCP offers the following services free of charge within this open call: Acute toxicity… Read more
Radislav Sedlacek participated in the panel discussion at EU-AMRI launch event
“Research infrastructures are perfectly positioned to co-work at the frontier of science and industry.”, said Radislav Sedlacek, Director of the Czech Centre for Phenogenomics and the former Chair of the ESFRI Health and Food Strategic Working Group at the EU-AMRI launch event, which took place on 5th April 2022 in Brussels. You can watch the… Read more
Вакансії для біженців з України
Czech Centre for Phenogenomics пропонує науковцям та лаборантам з України можливість займатися дослідницькою діяльністю в нашому центрі. Ми також вітаємо тих, хто зацікавлений у посаді лаборанта з догляду за лабораторними тваринами для якої не потрібно мати наукову освіту. Для отримання більш детальної інформації, будь ласка, відвідайте сторінку вакансій на нашому веб-сайті. Read more
Towards precision medicine and gene therapy – a new AV21 Strategy programme
Czech Centre for Phenogenomics is coordinating a new research programme “Towards precision medicine and gene therapy” of the AV21 Strategy. Our programme benefits from the synergistic expertise of all partners and creates a multidisciplinary consortium covering the areas of gene editing, organic chemistry of nucleic acid delivery systems, preclinical models of human diseases, and starting with neurosciences… Read more
Mice and genetic scissors help Czech scientists seek treatment for “angelic” children
On the occasion of the International Day of Rare Diseases Czech Centre for Phenogenomics in collaboration with BIOCEV and Czech Academy of Sciences issued a press release summarizing their research in the area of rare diseases. The press release (in English) is available on the BIOCEV website. The press release (in Czech) is available on… Read more
Mouse models from the Czech Centre for Phenogenomics help in researching Angelman’s syndrome
We are celebrating the International Angelman Day on 15th February. Angelman’s syndrome is an inherited disease of the central nervous system that causes severe physical and mental disabilities. The team of the Czech Center for Phenogenomics is engaged in research of Angelman’s syndrome (and other rare diseases) on mouse models created by us or already… Read more
Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern
The emergence of new SARS-CoV-2 variants that harbor mutations in the viral S protein raised concern about activity of current vaccines and therapeutic antibodies. CCP participated in the research study aiming to find new tools for COVID-19 therapy based on the novel monoclonal antibodies. The results were recently published in EBioMedicine belonging to the Lancet… Read more
Czech-Swiss project “SARS-Cov-2: understanding the entry, multi-organ spread and immune response in the context of vaccination and re-infection” received funding.
Our collaboration with Luca Varani’s lab from the Institute for Research in Biomedicine in Bellinzona in Switzerland will expand thanks to the grants of the Czech and the Swiss Science Foundations. Both foundations decided to fund our joint project “SARS-Cov-2: understanding the entry, multi-organ spread and immune response in the context of vaccination and re-infection”… Read more
Scientific Advisory Board met virtually
On Friday 21st January 2022, the Scientific Advisory Board met virtually and discussed with CCP management the achievements of 2021 and future directions of the Centre for the period 2022-2029. Besides the traditional reports about 2021 outcomes in research services, research and development of new methodologies, the presented highlights focused on: Cardiovascular comprehensive screening for… Read more