News
Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern
The emergence of new SARS-CoV-2 variants that harbor mutations in the viral S protein raised concern about activity of current vaccines and therapeutic antibodies. CCP participated in the research study aiming to find new tools for COVID-19 therapy based on the novel monoclonal antibodies. The results were recently published in EBioMedicine belonging to the Lancet… Read more
Czech-Swiss project “SARS-Cov-2: understanding the entry, multi-organ spread and immune response in the context of vaccination and re-infection” received funding.
Our collaboration with Luca Varani’s lab from the Institute for Research in Biomedicine in Bellinzona in Switzerland will expand thanks to the grants of the Czech and the Swiss Science Foundations. Both foundations decided to fund our joint project “SARS-Cov-2: understanding the entry, multi-organ spread and immune response in the context of vaccination and re-infection”… Read more
Scientific Advisory Board met virtually
On Friday 21st January 2022, the Scientific Advisory Board met virtually and discussed with CCP management the achievements of 2021 and future directions of the Centre for the period 2022-2029. Besides the traditional reports about 2021 outcomes in research services, research and development of new methodologies, the presented highlights focused on: Cardiovascular comprehensive screening for… Read more
New CCP e-Newsletter 2021
The first issue of our brand new online newsletter is available on https://phenogenomics.cz. We are delighted to share our recent achievements and updates on mouse phenogenomics, so from now on, the latest developments at CCP will be directly delivered to you via e-mail, with a dedicated website and interesting links for further reading. Enjoy reading… Read more
Season’s greetings and the best wishes for the New Year
We wish you all the best for the New Year and look forward to cooperating with you in 2022. Read more
CCP evaluated in the International peer-review of large research infrastructures in the Czech Republic in 2021
In the first half of 2021, the Ministry of Education, Youth and Sports organized an international peer-review of large research infrastructures in the Czech Republic, which results were published in December. The purpose of this evaluation was to obtain independent expert reviews about the performance of large research infrastructures. CCP confirmed its top level. According… Read more
Infrafrontier in the new ESFRI 2021 Roadmap
The updated ESFRI Roadmap was published this week. INFRAFRONTIER is mentioned as an example of ESFRI Research Infrastructures in response to emergencies, specifically to the covid-19 crisis. “INFRAFRONTIER rapidly evolved a broad portfolio of services to evaluate the potential of new anti-COVID-19 compounds and therapeutics on suitable humanized models as well as BSL3 laboratories for… Read more
CCP talk at final PATHBIO meeting
Radislav Sedlacek shared experience of the Czech Centre for Phenogenomics in preclinical development in his talk “Beyond standardized phenotyping pipeline: the path towards preclinical development” at the final PATHBIO meeting “Reproducibility and Translatability in Research: the Path forward”. The meeting took place on 3rd December, 2021 in Naples. The meeting was opened by a keynote… Read more
Sharing & archiving of genetically altered mice: opportunities for reduction and refinement
International experts on breeding, managing and archiving colonies gathered in the expert working group of the UK National Centre for the Replacement & Refinement & Reduction of Animals in Research has updated the document “Sharing & archiving of genetically altered mice: opportunities for reduction and refinement”. The updated document reflects how current best practices in… Read more
Three CCP members joined COST Actions
Jan Rozman joined the new COST Action CA20135 – Improving biomedical research by automated behaviour monitoring in the animal home-cage. The Action will assess the potential of these technologies, develop user guidelines and standard operating procedures and identify needs for further technological development. CCP will bring knowledge in preclinical testing in the stroke research field… Read more