Service

canSERV invites applications covering the entire range of the oncology developmental pipeline; supporting discoveries in fundamental research to translational science and personalised oncology.  canSERV welcomes excellent research applications addressing at least one of the four strategic goals of the Cancer Mission.  CCP provides following services under this call: Generation of precision cancer mouse models using… Read more

The new state-of-the-art BSL-3 laboratory for work with highly infectious viruses and bacteria in the Czech Republic was opened on 9 March at the Czech Centre for Phenogenomics (Institute of Molecular Genetics of the Czech Academy of Sciences in the BIOCEV centre). When it is fully operational, it will raise the level of Czech research… Read more

Are you interested in our preclinical services? Download our latest leaflet with an overview of services we provide to our users in the area of preclinical services. Read more

We would like to inform our users that CCP now offers automated single cell functional proteomics analysis on the Isoplexis platform enabling for single cell functional immunophenotyping or phospho-protein analysis. If you want to know more about the device and services available in CCP for your research please check the details at our immunology unit… Read more

To test substances that have succeeded in basic research and help them on the long journey from the test tube to the development of new drugs. This is the goal of the Centre for Preclinical Testing, funded by the Strategy of the Czech Academy of Sciences AV21. The centre is run in close collaboration of… Read more

The first call is divided into six main sections which are: Surveillance & Epidemic Risk Management; Understanding SARS-CoV-2 & Covid-19; Diagnostics; Therapeutics; Vaccines; and Social Sciences & Epidemiology. The call is multidisciplinary and open to all scientists both from academia and private sector, including the partners of the ISIDORe consortium. The users wishing to benefit… Read more

In the framework of the EUVEN COST Action the unique phenotyping infrastructure Czech Centre for Phenogenomics (CCP) will support researchers in searching for the novel utilization of venom-derived compounds and identifying their translational potential and identifying physiological functions of toxin compounds. CCP offers the following services free of charge within this open call: Acute toxicity… Read more

Ace2 knock-out model A number of promising COVID-19 therapies is focused on targeting the Ace2 receptor. Thus, it is desired to evaluate: the potential of Ace2 blocking to prevent viral entry into the cells unwanted off-target effects caused by Ace2 deficiency. Ace2 deficient mutant mice provide an excellent tool for these types of experiments. Tmprss2… Read more

In December 2020, Infrafrontier launched an attractive free-of-charge service for the biomedical research community fighting against the COVID-19 pandemic. The Infrafrontier call turned out to be the most successful open call of the consortium so far. 21 scientific institutions from eight countries applied to be one of the five research projects that an INFRAFRONTIER expert… Read more

Woo, X.Y., Giordano, J., Srivastava, A. et al. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nat Genet 53, 86–99 (2021). https://doi.org/10.1038/s41588-020-00750-6 Patient-derived xenografts (PDXs) are resected human tumors engrafted into mice for preclinical studies and therapeutic testing. It has been proposed that the mouse host affects tumor evolution during PDX engraftment and propagation, affecting… Read more