understanding
of the genetic basis for
human diseases
Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.
Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.
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Head h2
Head h3
Head 3 orange
Head 3 blue
Unordered list
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- Magnis felis ultrices torquent tortor convallis per et nunc erat ridiculus risus, ullamcorper ipsum vulputate sed integer praesent condimentum lobortis quam.
- Porttitor ante erat morbi et torquent commodo facilisis viverra consectetur lacinia, dui donec hac felis inceptos nam scelerisque ipsum auctor, integer euismod ultricies velit mus montes maecenas ligula taciti.
Ordered list
- Torquent natoque libero lectus dolor class amet ac dictumst ullamcorper phasellus hac dui ligula ut, eu metus non dis consectetur habitant efficitur molestie ultrices parturient finibus ante leo.
- Proin morbi maximus nam amet dui a per vivamus, nisi phasellus tincidunt cursus nullam natoque fermentum euismod, sollicitudin varius lorem scelerisque in odio diam.
- Ligula varius fusce netus tortor dis vivamus rhoncus efficitur, accumsan magna ut pellentesque tellus cras quam ultricies cursus, consectetur lectus per consequat lacinia placerat integer.
- Risus vestibulum vel tristique dolor iaculis praesent finibus suscipit placerat, maximus suspendisse eu natoque tincidunt facilisis curabitur fames curae, tempus congue parturient arcu interdum aptent mi ipsum.
Tables
| Item | Value |
|---|---|
| One item | 3 |
| Two item | 18 |
| Three item | 200 |
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Latest News
New interview about rare diseases
Interview with Radislav Sedláček, director of the Czech Centre of Phenogenomics, focused on RD factory you can find here: https://vzacni.cz/pacienti-nam-pomohou-posunout-nas-vyzkum-dal-rozhovor-s-doc-radislavem-sedlackem/
First round of RD factory proposal collection closed, new round is open!
The first round of nomination collection in RD factory Program was closed on December 6, 2024. Proposals received later will be submitted in the next round that will close for evaluation in June 2005.
Our colleagues participated in the public debate The Genome Era.
https://www.ceskatelevize.cz/porady/16550392373-doba-genova-s-danielem-stachem/
About Czech Centre for Phenogenomics
Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.
Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.
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Section 2
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Section 3
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